OBJECTIVETo analyze the status of reaching meridian research for the Chinese Matria Medica and to raise point-medicine method.

METHODTo review and analyze the studied situation of the corresponding relationships between "materials", as the constituents in the Chinese materia medica (CMM) as reaching meridian material foundation, and "image", as the function states of the zang-fu viscera, to investigate the problems and the measures to solve it.

RESULTThere are imprinting relationships among "materials", as the constituents alike metabolic pathway in the CMM as reaching meridian material foundation, and "image", as the function of the zang-fu viscera related with meridians, and "symptom", the states of them, retroacted, represented and explored by the corresponding meridianed constituents in the CMM as quantitative pharmacologic parameters,also modified by special acupuncture points, finally to establish the new method of reaching meridian according to meridian point-medicine action and also to investigate the relations between the constituents in the CMM and network targets of disease as to kill two birds with one arrow.

CONCLUSIONThere are imprinting relationships among "materials", "image", "symptom" versus CMM, zang-fu viscera function related with meridians, their function status respectively, which are modified by acupuncture merisian points. The point-medicine method for assuring reaching meridian is the most simple way to investigate reaching meridian for CMM, is also a important way to investigate visceral and meridianal manifestations.