Chemical constituents from ethyl acetate extract of Artemisia rupestris.
- Author:
Feng-Xia CUI
1
;
Chen ZHANG
;
Yong JIANG
;
Peng-Fei TU
Author Information
1. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing 100191, China. cfx_1990@126.com
- Publication Type:Journal Article
- MeSH:
Artemisia;
chemistry;
Drugs, Chinese Herbal;
chemistry;
isolation & purification;
Mass Spectrometry;
Molecular Structure
- From:
China Journal of Chinese Materia Medica
2013;38(11):1757-1759
- CountryChina
- Language:Chinese
-
Abstract:
Chemical constituents of ethyl acetate extract of Artemisia rupestris were isolated and purified by various chromatographic methods, including silica gel, ODS and Sephadex LH-20. Their structures were elucidated on the basis of spectroscopic data analysis. 12 compounds were separated from A. rupestris and their structures were identified as 5,4'-dihydroxy -3,6,7-trimethoxy flavone (1), R-(-) -vestitol (2), tricin (3), chrysoeriol (4), 3-indole carboxylic acid (5), esculetin (6), apigenin (7), luteolin (8), trans-caffeic acid (9), casticin (10), chrysosptertin B (11) and artemetin (12). Compound 2 was obtained from the genus Artemisia for the first time, and compounds 1-6 and 9 were separated from this plant for the first time.