A clinical study on manshuailing oral liquid in treating elder patients with congestive heart failure of type heart and kidney yang deficiency.
- Author:
Ding-you YANG
1
;
Xing-li WU
;
Hao XU
;
Xue-zhong DUAN
;
Shi-wen WANG
;
Zhi-zheng LU
Author Information
- Publication Type:Clinical Trial
- MeSH: Administration, Oral; Adult; Aged; Cardiotonic Agents; therapeutic use; Combined Modality Therapy; Diagnosis, Differential; Digoxin; therapeutic use; Drug Combinations; Drugs, Chinese Herbal; administration & dosage; isolation & purification; therapeutic use; Female; Heart Failure; drug therapy; physiopathology; Heart Function Tests; Humans; Hydrochlorothiazide; therapeutic use; Isosorbide Dinitrate; therapeutic use; Male; Medicine, Chinese Traditional; Middle Aged; Phytotherapy; Plants, Medicinal; chemistry; Sodium Chloride Symporter Inhibitors; therapeutic use; Vasodilator Agents; therapeutic use; Yang Deficiency; drug therapy
- From: China Journal of Chinese Materia Medica 2003;28(11):1091-1093
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the clinical effect of manshuailing oral liquid on patients with congestive heart failure of type heart and kidney Yang deficiency.
METHOD90 patients of heart failure were randomly divided into 2 groups. 45 cases in the routine treatment group (RT) received general therapy including diuretics and digitalis, and 45 cases in the Chinese herb medicine group (CH) were treated basically with the above medicine, with additional manshuailing oral liquid. The clinical effect was summarized 6 weeks after treatment.
RESULTTotal effect rate was 82.2% and 62.2% in CH and RTgroup respectively. Compared with pretreatment, heart function including stroke volume (SV), stroke volume index (SVI), cardiac index (CI), shorten rate of left ventricular short axe (deltaD%), distance of inter-ventricular septal to mitral valve (EPSS) were all improved significantly in both groups (P < 0.05 or P < 0.01), and with even better effects in the CH group than the RT group (P < 0.05 or P < 0.01), except the SV.
CONCLUSIONManshuailing oral liquid can alleviate clinical symptom, decreased EPSS, increase deltaD% and improve heart function.
