Studies on the effect of dihydromyricetin on antilipid-peroxidation.
- Author:
Gui-xia HE
1
;
Wei-li YANG
;
Gang PEI
;
Yong-hua ZHU
;
Fang-lu DU
Author Information
- Publication Type:Journal Article
- MeSH: Ampelopsis; chemistry; Animals; Antioxidants; isolation & purification; pharmacology; Brain; metabolism; Dose-Response Relationship, Drug; Flavonols; isolation & purification; pharmacology; Lipid Peroxidation; drug effects; Liver; metabolism; Male; Malondialdehyde; metabolism; Mitochondria; metabolism; Mitochondrial Swelling; drug effects; Myocardium; metabolism; Plants, Medicinal; chemistry; Rats
- From: China Journal of Chinese Materia Medica 2003;28(12):1188-1190
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the effects of Dihydromyricetin (DMY) on antilipid-peroxidation.
METHODThe antilipid-peroxidation of DMY on heart, liver, brain tissue homogenate and mitochondria was measured by the determination of malondiadehyde (MDA) induced by Fe2+ -Vit C, Fe2+ -H2O2, Fe-Cys with TBA spectrometric method.
RESULTDMY could inhibit the lipid peroxidation of homogenate and mitochondria. The inhibition exhibited concentration-dependent manner.
CONCLUSIONDMY has good antilipid-peroxidation effect, which is worth studing further.
