Effect of ginsenoside Rg2 on chemical myocardial ischemia in rats.
- Author:
Jian-ming TIAN
1
;
Hao LI
;
Jin-mei YE
;
Wei-fang GUO
;
Lon-yun LI
;
Li-ping WANG
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Creatine Kinase; metabolism; Electrocardiography; drug effects; Female; Ginsenosides; isolation & purification; pharmacology; Isoproterenol; Male; Malondialdehyde; metabolism; Myocardial Ischemia; chemically induced; pathology; physiopathology; Myocardium; pathology; Panax; chemistry; Pituitary Hormones, Posterior; Plant Leaves; chemistry; Plants, Medicinal; chemistry; Rats; Rats, Wistar; Sodium Nitrite; Superoxide Dismutase; metabolism
- From: China Journal of Chinese Materia Medica 2003;28(12):1191-1192
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the protective effect of Ginsenoside Rg2 on Chemical myocardial ischemia.
METHODThe models of myocardial ischemia were built in rats with isoproterenol, sodium nitrite,pituitrin. Ginsenoside Rg2 (iv 2.5, 5.0, 10.0 mg x kg(-1)) were intravenously administered.
RESULTGinsenoside Rg2 could improve the abnormal electrocardiogram (ECG), reduce the arca of myocardial ischemia and improve the abnormal zymologic value of myocardial.
CONCLUSIONGinsenoside Rg2 has inhibitory function on myocardialischemia.
