Studies on the flavonoids in herb from Scutellaria barbata.

Author: Wen-shu WANG ¹ ; Ya-wei ZHOU ; Yun-hua YE ; Nan DU
Author Information

1. Key Laboratory of Bioorganic and Molecular Engineering, Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.
Publication Type:Journal Article
MeSH: Apigenin; analogs & derivatives; chemistry; isolation & purification; Flavonoids; chemistry; isolation & purification; Glucuronates; chemistry; isolation & purification; Plants, Medicinal; chemistry; Scutellaria; chemistry
From: China Journal of Chinese Materia Medica 2004;29(10):957-959
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo study flavonoids in Scutellaria barbata and elucidate their structures.
METHODCompounds were isolated and purified by normal column chromatography, paper thin layer chromatography and Sephadex chromatography. The chemical structures were elucidated by ESI mass and NMR spectra.
RESULTFive flavonoids were isolated from S. barbata and identified as apigenin (1), luteolin (2), ethyl-7-O-apigenin-glucuronate (3), apigenin-7-O-beta-glucoside (4), and apigenin-7-O-neohesperidoside (5), in addition to benzyaldehyde (6).
CONCLUSIONFlavonoidglycoside (3), (4) and (5) were isolated from S. barbata for the first time.