Study on the effects of two kinds of cactus polysaccharide on erythrocyte membrane protein and fluidity of the lipid in S180 mice.
- Author:
Yu-bin JI
1
;
Chen-feng JI
;
Xiang ZOU
;
Shi-yong GAO
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Anion Exchange Protein 1, Erythrocyte; metabolism; Antineoplastic Agents, Phytogenic; administration & dosage; isolation & purification; pharmacology; Dose-Response Relationship, Drug; Erythrocyte Membrane; metabolism; physiology; Male; Membrane Fluidity; drug effects; Mice; Opuntia; chemistry; Plants, Medicinal; chemistry; Polysaccharides; administration & dosage; isolation & purification; pharmacology; Sarcoma 180; metabolism
- From: China Journal of Chinese Materia Medica 2004;29(10):967-970
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the effects of two kinds of cactus polysaccharide on Band 3 protein, cross-linking protein and lipid fluidity of erythrocyte membrane in S180 mice.
METHODThe membrane protein content was analysed by SDS-PAGE. Lipid fluidity was measured by Skinitzky method.
RESULTThe two kinds of cactus polysaccharide increased the content of Band 3 protein and decreased the content of cross-linking protein, raised the lipid fluidity. While the effect of median dose group of medical cactus polysaccharide is very remarkable (P < 0.01), the effect of high dose group of edible cactus polysaccharide is very remarkable (P < 0.01).
CONCLUSIONBy improving the erythrocyte membrane function of tumor-mice, they enhanced the immune function, which may be one of anti-tumor mechanisms.
