Clinical observation of influence of warfarin on post-operative bleeding after tooth extraction in the elderly.
- Author:
Wen-ying WANG
1
;
Nian-hui CUI
;
En-bo WANG
;
Wei ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Age Factors; Aged; Aged, 80 and over; Anticoagulants; administration & dosage; adverse effects; Female; Humans; International Normalized Ratio; Male; Middle Aged; Postoperative Hemorrhage; etiology; Tooth Extraction; adverse effects; Warfarin; administration & dosage; adverse effects
- From: Chinese Journal of Stomatology 2013;48(7):385-387
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the feasibility of continuing warfarin when international normalized ratio (INR) was less than 2.5 before tooth extraction in the elderly.
METHODSOne hundred elderly outpatients with prolong use of warfarin and maintaining INR < 2.5 before tooth extraction served as observation group, 200 elderly outpatients without taking anticoagulant and antiplatelet medicine served as control group. All the patients underwent a single non-impacted tooth extraction. Postoperative bleeding at different time was observed.
RESULTSThere was significant difference in postoperative bleeding at 5, 10, 30 min, 24 h after extraction and there was no significant difference at 48 h between control group and observation group (P < 0.05) and no bleeding was found in either group at 48 h (incidence of bleeding were 0%).
CONCLUSIONSIt was feasible to continue warfarin for the elderly maintaining INR < 2.5 undergoing a single non-impacted tooth extraction by monitoring postoperative bleeding and hemostatic treatment measures.
