Clinical oberservation of influence of wafarin on post-operative bleeding after tooth extraction in the elderly

VernacularTitle:华法林对老年人拔牙术后出血影响的临床观察
Author: Wen-Ying WANG ¹ ; Nian-Hui CUI ; En-Bo WANG ; Wei ZHANG
Author Information

1. 100081,北京大学口腔医学院·口腔医院口腔颌面外科
Keywords: Warfarin; Aged; Tooth extraction; Bleeding time
From: Chinese Journal of Stomatology 2013;48(7):385-387
CountryChina
Language:Chinese
Abstract: Objective To investigate the feasibility of continuing warfarin when international normalized ratio (INR) was less than 2.5 before tooth extraction in the elderly.Methods One hundred elderly outpatients with prolong use of warfarin and maintaining INR ＜ 2.5 before tooth extraction served as observation group,200 elderly outpatients without taking anticoagulant and antiplatelet medicine served as control group.All the patients underwent a single non-impacted tooth extraction.Postoperative bleeding at different time was observed.Results There was significant difference in postoperative bleeding at 5,10,30 min,24 h after extraction and there was no significant difference at 48 h between control group and observation group(P ＜0.05)and no bleeding was found in either group at 48 h(incidence of bleeding were 0％).Conclusions It was feasible to continue warfarin for the elderly maintaining INR ＜ 2.5 undergoing a single non-impacted tooth extraction by monitoring postoperative bleeding and hemostatic treatment measures.