Curative effect of stereotactic 186Re endocavitary irradiation on cystic craniopharyngioma.
- Author:
Chuan-jun GUO
1
;
Yan-chun WANG
;
Zhen-hu ZHOU
;
Jian-xin ZHU
;
Zhong-min LI
;
Chang-li GUO
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Brachytherapy; methods; Child; Child, Preschool; Craniopharyngioma; radiotherapy; Cysts; radiotherapy; Female; Follow-Up Studies; Humans; Male; Middle Aged; Pituitary Neoplasms; radiotherapy; Radioisotopes; therapeutic use; Rhenium; therapeutic use; Stereotaxic Techniques; Treatment Outcome; Young Adult
- From: Chinese Journal of Oncology 2010;32(7):548-550
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the treatment results of stereotactic (186)Re intracavitary irradiation in the patients with craniopharyngioma.
METHODSNineteen patients were treated with stereotactic (186)Re intracavitary irradiation, including 12 males and 7 females (average age, 37.2 years). Among them 12 patients had a solitary cyst, whereas 7 patients with mixed structure (e.g., a large cyst with a small solid portion). The mean volume of the cystic portion of the tumor before irradiation was 8390 mm(3).
RESULTSThe patients were followed up for 6 months to 3 years. The retraction of the cyst was complete in 7 patients, cyst volume decreased more than 50% in 5 patients and less than 50% in 7 cases. Among the 8 patients with visual acuity deficit before irradiation, 5 were improved. No hypopituitarism occurred in patients with normal pituitary function before treatment. One of the 4 patients with hypopituitarism was improved, 3 of the 5 patients with diabetes insipidus was improved.
CONCLUSIONStereotactic (186)Re endocavitary irradiation for the treatment of cystic craniopharyngioma is a safe and effective procedure.
