Expression of trophinin in human oocytes and preimplantation embryos.

Author: Hua-Yun WANG ¹ ; Fu-Qi XING ; Shi-Ling CHEN
Author Information

1. Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Publication Type:Journal Article
MeSH: Blastocyst; metabolism; Cell Adhesion Molecules; biosynthesis; Female; Fluorescent Antibody Technique, Indirect; Humans; Microscopy, Confocal; Oocytes; metabolism; Pregnancy
From: Journal of Southern Medical University 2008;28(1):122-124
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo investigate the significance of trophinin expression in human oocytes and preimplantation embryos.
METHODSThe expression of trophinin in 9 human oocytes, 16 blastomeres and 12 blastocysts were detected by indirect immunofluorescence assay and observed under laser scanning confocal microscope.
RESULTSHuman oocytes, blastomeres and blastocysts were all positive for trophinin expression, and the positivity intensified significantly in the course of the embryonic development (P<0.05).
CONCLUSIONTrophinin may play an important role in human embryo implantation by mediating homophilic adhesion between the embryo and the endometrium during the implantation window.