Chemistry and pharmacology of 4-hydroxylonchocarpin: a review.
10.1007/s11655-013-1195-7
- Author:
Victor KUETE
1
;
Jaures A K NOUMEDEM
;
Frederic NANA
Author Information
1. Department of Biochemistry, Faculty of Science, University of Dschang, Yaounde, Cameroon. kuetevictor@yahoo.fr
- Publication Type:Journal Article
- MeSH:
Anti-Bacterial Agents;
chemistry;
pharmacology;
Antifungal Agents;
chemistry;
pharmacology;
Biosynthetic Pathways;
drug effects;
Cell Death;
drug effects;
Flavones;
biosynthesis;
chemistry;
pharmacology;
Humans
- From:
Chinese journal of integrative medicine
2013;19(6):475-480
- CountryChina
- Language:English
-
Abstract:
4-hydroxylonchocarpin (LCP) or 2',4-dihydroxy-3',4'-(2,2-dimethylchromene) chalcone is a chalcone of the class flavonoid, with a molecular weight of 322 g/mol mostly isolated in the family Moraceae and Leguminosae. LCP was reported to have a variety of pharmacological activities such as antibacterial, antifungal, anticancer, anti-reverse transcriptase, antitubercular, antimalarial, anti-inflammatory, ornitnine decarboxylase activity and antioxidant. The hemisynthesis of the compound has been described. The present review was undertaken to bring out together the knowledge on LCP, and can serve as the start point for future research and valorization accomplishments.
