Study on chromatography-efficacy relation of Zanthoxylum nitidum on gastric cancer cells.
- Author:
Qingrong SHEN
1
;
Huixue HUANG
;
Honghong WANG
;
Lijuan CAO
;
Kan FENG
;
Yuehua YE
;
Huagang LIU
Author Information
- Publication Type:Journal Article
- MeSH: Antineoplastic Agents, Phytogenic; analysis; pharmacology; Cell Line, Tumor; Cell Proliferation; drug effects; Chromatography, High Pressure Liquid; methods; Drugs, Chinese Herbal; analysis; pharmacology; Humans; Stomach Neoplasms; drug therapy; physiopathology; Zanthoxylum; chemistry
- From: China Journal of Chinese Materia Medica 2011;36(19):2693-2696
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo develop a method for elucidating " chromatography-efficacy" relation of the extract of Zanthoxylum nitidum on the gastric cancer cells.
METHODAfter obtaining the tumor inhibition rate and fingerprint peak data through MTT and HPLC, "chromatography-efficacy" relation was established by an appropriate statistical method.
RESULTThe gastric cancer "chromatography-efficacy" relation of Z. nitidum was established by step-back technique.
CONCLUSIONThe "chromatography-efficacy" relation has statistically significant and practical significance, so it has reference value in some way.
