Chemical constituents from root bark of Tripterygium hypoglaucum.
- Author:
Zhenzhen LIU
1
;
Ronghua ZHAO
;
Zhongmei ZOU
Author Information
- Publication Type:Journal Article
- MeSH: Chromatography; methods; Diterpenes; chemistry; isolation & purification; Fatty Acids, Unsaturated; chemistry; isolation & purification; Magnetic Resonance Spectroscopy; methods; Mass Spectrometry; methods; Oleanolic Acid; chemistry; isolation & purification; Organic Chemicals; chemistry; isolation & purification; Palmitic Acid; chemistry; isolation & purification; Plant Roots; chemistry; metabolism; Sitosterols; chemistry; isolation & purification; Stearic Acids; chemistry; isolation & purification; Tripterygium; chemistry; metabolism; Triterpenes; analysis; chemistry; isolation & purification
- From: China Journal of Chinese Materia Medica 2011;36(18):2503-2506
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate chemical constituents of the root bark of Tripterygium hypoglaucum.
METHODCompounds were isolated by column chromatography on silica gel and Sephadex LH-20, and their structures were identified on the basis of spectral data (MS, 1H-NMR and 13C-NMR).
RESULTTwelve compounds were isolated and identified as friedelin (1), 3-oxo-olean-9(11),12-diene (2), canophyllal (3), 3-acetoxy oleanolic acid (4), triptophenolide (5), triptonoterpene methyl ether (6), tricosanoic acid (7), beta-sitosterol (8), stearic acid (9), glut-5-en-3beta,28-diol (10), palmitic acid (11) and daucostorol (12).
CONCLUSIONCompounds 1, 2, 3, 7 and 10 were isolated from T. hypoglaucum and 7 from the genus Tripterygium for the first time.
