Studies on metabolites from marine microorganism Aspergillus terreus collected from nature reserve region of mangrove.
- Author:
Yi SHEN
1
;
Jianhua ZOU
;
Jungui DAI
Author Information
- Publication Type:Journal Article
- MeSH: Alkaloids; chemistry; isolation & purification; metabolism; Aspergillus; chemistry; metabolism; Ceramides; chemistry; isolation & purification; metabolism; Culture Media; chemistry; metabolism; Esters; chemistry; isolation & purification; metabolism; Isocoumarins; chemistry; isolation & purification; metabolism; Mycelium; chemistry; metabolism; Propylene Glycols; chemistry; isolation & purification; metabolism; Rhizophoraceae; microbiology; Steroids; chemistry; isolation & purification; metabolism
- From: China Journal of Chinese Materia Medica 2011;36(18):2515-2519
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo search for new antitumor active lead compounds from marine microorganism.
METHODA marine strain, Aspergillus terreus, was cultured and up-scaled in artificial seawater media, from which the metabolites were isolated and elucidated by using modern spectroscopy techniques.
RESULTTwelve compounds were isolated from mycelia and fermentation broth of A. terreus.
CONCLUSIONCompounds 1-4 were steroids, compounds 5-8 were organic acids and esters, compound 9 was an alkaloid, compound 10 was an isocoumarin, compound 11 was ceramide, compound 12 was propenyl cyclic pentanediol.
