Study on adverse drug reaction in Yuixngcao injection literatures.
- Author:
Zhifei WANG
1
;
Yanming XIE
;
Yongyan WANG
Author Information
1. Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China. wzhftcm@163.com
- Publication Type:Journal Article
- MeSH:
Drug Therapy, Combination;
Drug-Related Side Effects and Adverse Reactions;
Drugs, Chinese Herbal;
administration & dosage;
adverse effects;
Humans;
Injections
- From:
China Journal of Chinese Materia Medica
2011;36(20):2862-2865
- CountryChina
- Language:Chinese
-
Abstract:
Yuxingcao injection was suspended by China State Food and Drug Administration in 2006 for its severe adverse reaction in clinical practice. Althoug there are many real factors resulted in Yuxingcao injection's adverse reaction, some confounding factors should not be ignored. This study searched different kinds of related literatures and found out irregularity in defining dosage, disuses courses, indications and administration approach, which were the potential factors that caused the reported adverse drug reaction for Yuxingcao injection. And 97.8% adverse drug reaction in Yuxingcao injection happened 30 minutes after patients received administion, hence, observing patients'reaction in the first 30 minutes should be very important to prevent severe adverse drug reaction.
