Diagnostic value of transbronchial needle aspiration combined with transesophageal endoscopic ultrasound-guided fine needle aspiration in mediastinal and pulmonary hilar lesions.
- Author:
Xiao-Yan LI
1
;
Gui-Yu CHENG
;
Zhi-Hui ZHANG
;
Ning LÜ
;
Yue-Ming ZHANG
;
Shuang-Mei ZOU
;
Li-Yan XUE
;
Lei ZHANG
;
Xiao-Guang NI
;
Shao-Qing LAI
;
Shun HE
;
Gui-Xiang YU
;
Feng-Huan JU
;
Hua-Ying XUN
;
Rong-Rong CHENG
;
Gui-Qi WANG
Author Information
- Publication Type:Journal Article
- MeSH: Adenocarcinoma; diagnostic imaging; pathology; Adolescent; Adult; Aged; Aged, 80 and over; Biopsy, Fine-Needle; methods; Biopsy, Needle; Carcinoma, Squamous Cell; diagnostic imaging; pathology; Endosonography; methods; Female; Humans; Lung Neoplasms; diagnostic imaging; pathology; Lymph Nodes; diagnostic imaging; pathology; Lymphatic Metastasis; Male; Mediastinal Neoplasms; diagnostic imaging; pathology; secondary; Mediastinum; Middle Aged; Neoplasm Staging; Small Cell Lung Carcinoma; diagnostic imaging; pathology; Young Adult
- From: Chinese Journal of Oncology 2009;31(7):536-540
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the value of transbronchial needle aspiration (TBNA) combined with transesophageal endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) in the diagnosis of mediastinal and pulmonary hilar lesions as well as in the lymph node staging (N staging) of lung cancer.
METHODS129 patients with mediastinal and pulmonary hilar lesions underwent either TBNA or EUS-FNA with cytological needle aspiration. The samples obtained from TBNA or EUS-FNA were examined by both cytologiy and histopathology.
RESULTSOf the 129 patients, 59 underwent TBNA and 70 EUS-FNA. The diagnostic rate were 84.7% (50/59) by TBNA and 94.3% (66/70) by EUS-FNA, resepectively. The diagnosis of 116 (89.9%) patients were confirmed by either TBNA or EUS-FNA. The pathological and cytological diagnostic rates were 92.2% (107/116) and 88.0% (102/116), resepectively. The diagnostic rate was elevated by 8.4% (9/107) through pathological examination. The histological classification rates by cytological and pathological examination were 73.8% (76/116) and 89.3% (92/103), respectively. The diagnostic rate of histological classification was elevated by 35.5% (27/76) through pathological examination.
CONCLUSIONThe combination of TBNA and EUS-FNA can improve the diagnostic rate for wider mediastinal and pulmlonary hilar lesions. Pathological examination of the samples obtained from the TBNA and EUS-FNA can elevate not only the rate of diagnosis but also the rate of histological classification.
