Determination of plasma homocysteine in oligospermia and/or asthenospermia patients.
- Author:
Yi-Feng GE
1
;
Chun-Hui WANG
;
Luo-Xuan OUYANG
;
Yong SHAO
;
Bing YAO
;
Xin-Yi XIA
;
Xue-Jun SHANG
;
Yu-Feng HUANG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Asthenozoospermia; blood; Case-Control Studies; Homocysteine; blood; Humans; Male; Oligospermia; blood; Sperm Count; Sperm Motility
- From: National Journal of Andrology 2008;14(12):1112-1114
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo detect the level of fasting plasma homocysteine (Hcy) in patients with oligospermia and/or asthenospermia and to investigate its clinical significance.
METHODSSemen quality analyses and fasting plasma Hcy determination were performed for 86 infertility patients (21 with oligospermia, 32 with asthenospermia and 33 with oligo-asthenospermia) and 19 normal fertile volunteers. The results were compared.
RESULTSThe level of plasma Hcy was significantly higher in the infertility patients than in the normal controls (P < 0.05) and negatively correlated with sperm concentration (r = -0.433, P < 0.01), the percentage of grade a sperm (r = -0.303, P < 0.05) and the percentage of grade a+b sperm (r = -0.339, P < 0.01).
CONCLUSIONThe increased level of human plasma Hcy directly or indirectly affects spermatogenesis and correlates negatively with oligospermia and/or asthenospermia.
