A comparative study of the effects of Acanthopanacis senticosi injection, theophylline and caffeine on human sperm mobility in vitro.
- Author:
Wei WU
1
;
Ji-hong LIU
;
Chun-ping YIN
;
Chuan-hua ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Caffeine; pharmacology; Drugs, Chinese Herbal; pharmacology; Eleutherococcus; chemistry; Humans; In Vitro Techniques; Male; Sperm Motility; drug effects; Theophylline; pharmacology
- From: National Journal of Andrology 2009;15(3):278-281
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo compare the effect of Acanthopanacis senticosi injection, theophylline and caffeine on human sperm mobility in vitro.
METHODSWe incubated the sperm aseptically obtained by masturbation from 12 asthenospermia men and treated by swim-up technique in Acanthopanacis senticosi injection (10 g/L), theophylline (3 mmol/L) and caffeine (7 mmol/L) respectively, and detected various sperm parameters with the computer-assisted sperm analysis (CASA) system at 0 h, 1 h and 3 h.
RESULTSAcanthopanacis senticosi injection significantly increased sperm motility, the percentage of progressive motile sperm, straight line velocity (VSL) and curvilinear velocity (VCL) as compared with theophylline and caffeine (P < 0.05).
CONCLUSIONAcanthopanacis senticosi injection can activate the mobility of human sperm in vitro.
