Diagnostic value of lesion-directed prostate biopsy under TRUS in early detection of prostate cancer.
- Author:
Jiang ZHU
1
;
Xue-Ming LIU
;
Chuan-Jun DU
;
Zhe-Wei ZHANG
;
Yi-Qing QIU
;
Yu GONG
;
Jing-Rui LIU
;
Yu-Rong HONG
;
Zhi-Yan LUO
;
Yong ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Aged, 80 and over; Biopsy; methods; Humans; Male; Middle Aged; Prostate; diagnostic imaging; pathology; Prostatic Neoplasms; diagnosis; diagnostic imaging; pathology; Ultrasonography, Interventional
- From: National Journal of Andrology 2009;15(5):437-440
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate lesion-directed biopsy in improving the detection rate of early prostate cancer (PCa) and in differentiating PCa from other prostate pathological changes.
METHODSWe performed TRUS-guided prostate biopsy for 95 patients suspected of PCa, each subjected to extended random biopsy plus lesion-directed biopsy, and analyzed the sonographic characteristics and pathological findings.
RESULTSPCa was detected in 35 of the patients (36.8%), including 16 hypoechoic (45.7%), 4 hyperechoic (11.4%), 10 isoechoic (28.6%) and 5 mixed hetero-echoic lesions (14.3%). Of the 35 PCa cases, 17 (46.2%) were within T2b, 70.6% (12/17) of which were detected by lesion-directed biopsy and 29.4% (5/17) by sextant biopsy, the former obviously higher than the latter (P < 0.05).
CONCLUSIONLesion-directed prostate biopsy under TRUS can significantly improve the early diagnosis of prostate cancer, increase convenience and reduce patients' pain, but is not sufficient to replace traditional sextant biopsy.
