B-cell lymphoma/leukemia-2 and benign prostatic hyperplasia.
- Author:
Min-Dao ZHANG
1
;
Yong-Ning ZHAO
;
Li-Wen AN
Author Information
1. Graduate of Grade 2006, Heilongjiang University of Chinese Medicine, Harbin, Heilongjiang 150040, China. zhangmindao1981@163.com
- Publication Type:Journal Article
- MeSH:
Animals;
Apoptosis;
Humans;
Male;
Mice;
Prostatic Hyperplasia;
genetics;
metabolism;
Proto-Oncogene Proteins c-bcl-2;
genetics;
Rats
- From:
National Journal of Andrology
2009;15(5):452-454
- CountryChina
- Language:Chinese
-
Abstract:
The B-cell lymphoma/leukemia-2 (Bcl-2) gene is an important member of the Bcl-2 family, a type of protein that plays an important role in the process of cell apoptosis. Bcl-2 does not change the rate of cell proliferation, but prolongs the life and increases the number of cells by counteracting a series of apoptosis. In the recent years, more and more evidence has shown a close correlation of the Bcl-2 gene with the development and progression of benign prostatic hyperplasia (BPH), a disease whose mechanism is not yet fully understood but is drawing more and more attention towards the role of cell apoptosis.
