Current status and prospects of biobutanol manufacturing technology.
- Author:
Yang GU
1
;
Yu JIANG
;
Hui WU
;
Xudong LIU
;
Zhilin LI
;
Jian LI
;
Han XIAO
;
Zhaobing SHEN
;
Jingbo ZHAO
;
Yunliu YANG
;
Weihong JIANG
;
Sheng YANG
Author Information
1. Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200032, China.
- Publication Type:Journal Article
- MeSH:
Biofuels;
Butanols;
metabolism;
Clostridium;
genetics;
metabolism;
Clostridium beijerinckii;
genetics;
metabolism;
Fermentation;
Genetic Engineering;
methods;
Industrial Microbiology;
methods;
trends
- From:
Chinese Journal of Biotechnology
2010;26(7):914-923
- CountryChina
- Language:Chinese
-
Abstract:
Butanol is not only an important chemical feedstock but also expected to become a new generation biofuel. Thus, biological butanol production using renewable feedstocks has attracted renewed attention due to the worries of global oil supply and its impact on social and economic development. However, compared with petrochemical-derived butanol, biological butanol production is still not economically competition, because of its major drawbacks: high cost of the feedstocks, low butanol concentration in the fermentation broth and the co-production of low-value byproducts acetone and ethanol. Recently, Shanghai cooperative bio-butanol group (SCBG) developed a simple-to-complex technical route to improve bio-butanol production with a focus on: increasing butanol ratio in the solvent through metabolic engineering of Clostridia spp.; introducing and optimizing the butanol synthetic pathway in the species with high butanol tolerance; overcoming the glucose repression effect to utilize low-cost non-grain based feedstocks. SCBG believes that, through extensive domestic and international industry-university-research cooperation, a sustainable and economically viable process for biological butanol production can be established in the near future.
