Studies on xenogenic acellular dermal matrix as a filling material.
- Author:
Mingli ZHANG
1
;
Ying WANG
;
Dawei WANG
;
Yingen PAN
;
Jiangping CHEN
Author Information
- Publication Type:Case Reports
- MeSH: Animals; Biocompatible Materials; metabolism; Cleft Lip; surgery; Dermis; physiology; transplantation; ultrastructure; Female; Forearm; abnormalities; surgery; Graft Survival; physiology; Humans; Male; Microscopy, Electron; Rabbits; Skin Transplantation; methods; Subcutaneous Tissue; surgery; Swine; Transplantation, Heterologous
- From: Chinese Journal of Plastic Surgery 2002;18(5):263-265
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the biological reaction of swine acellular dermal matrix as a filling material for body surface deformity.
METHODSXenogenic acellular dermal matrix was implanted into the hypoderm of rabbits. The implants were measured and observed with pathological and transmission electron microscopic technique at regular times. The results were compared with implantation of autologous dermis and swine dermis.
RESULTSThe implanted xenogenic acellular dermal matrix and autologous dermis had slight inflammatory reaction. At 2 weeks there were fibroblasts and capillaries in the implants. The absorptivity of the xenogenic acellular dermal matrix was lower than the swine dermis. The xenogenic acellular dermal matrix was used in 2 clinical cases and obtained good result.
CONCLUSIONThe xenogenic acellular dermal matrix is an ideal material with good compatibility feature and low absorptivity.
