Impact of attack frequency and therapy strategies on outcome of patients with vasovagal syncope
10.3760/cma.j.issn.0253-3758.2012.12.008
- VernacularTitle:发作频率不同的血管迷走性晕厥预后分析
- Author:
Dan-Tong SHEN
1
;
Zhong-Qiu LIN
;
Zhi-Quan XIE
;
Yu-Yu ZHAN
;
Yong LUO
;
Yi-Xin ZHONG
;
Zhi-Liang LI
Author Information
1. 510010,广州军区广州总医院干部病房四科
- Keywords:
Vasovagal syncope;
Cross-sectional studies;
Prognosis
- From:
Chinese Journal of Cardiology
2012;40(12):1016-1019
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the impact of attack frequency as well as therapy strategies on outcome of patients with vasovagal syncope (VVS).Methods A total of 159 patients (aged from 15-59 years old) with VVS were included in this study.Patients were divided into low frequency (< 3) group (n =95) and high (≥3) frequency group (n =64) according to the attack frequency in the past 5 years at the primary survey.Patients received one of the three therapies:no treatment,physical therapy,and comprehensive treatment.All cases were followed up with telephone or outpatient visit for 24 months.Results Incidence of syncope was significantly higher in the high frequency group and in the low frequency group [40.6% (26/64) vs.11.6% (11/95),P <0.01].The overall improvement rate was significantly higher in the low frequency group than that of high frequency group (P < 0.01).Improvement rate was significantly higher in the physical therapy subgroup and the comprehensive treatment subgroup than no treatment subgroup for patients with low attack frequency [81.8% (27/33) vs.47.1% (8/17),P < 0.05 ; 82.2% (37/45) vs.47.1% (8/17),P < 0.05],and in comprehensive treatment subgroup than in physical therapy subgroups observed between and [62.2% (28/45) vs.31.6% (6/19),P < 0.05] for patients with high attack frequency.Conclusion Outcome is related to previous attack frequency for patients with VVS,physical therapy is effective for reducing the recurrence rate of syncope in VVS patients with low attack frequency while physical therapy combined with pharmacotherapy should be applied for VVS patients with high attack frequency to improve outcome.