Progress of the micronucleus test in the field of molecular cancer epidemiology.
- Author:
Huadong XU
1
;
Guang JIA
2
Author Information
1. Department of Occupational and Environmental Health Sciences, School of Public Health, Peking University, Beijing 100191, China.
2. Department of Occupational and Environmental Health Sciences, School of Public Health, Peking University, Beijing 100191, China. Email:jiaguangjia@bjmu.edu.cn.
- Publication Type:Journal Article
- MeSH:
Apoptosis;
Biomarkers;
Carcinogens;
Chromosome Aberrations;
Cohort Studies;
DNA Damage;
DNA Repair;
Early Detection of Cancer;
Genetic Predisposition to Disease;
Humans;
Micronucleus Tests;
Micronutrients;
Molecular Epidemiology;
Mutation;
Neoplasms
- From:
Chinese Journal of Preventive Medicine
2015;49(1):93-97
- CountryChina
- Language:Chinese
-
Abstract:
The micronucleus test (MNT) can be used to detect multiple genetic end points simultaneously, including chromosome aberration, mis-repaired DNA damage, apoptosis, parts of mutation and so on, which MNT has been an important part of the study of cancer epidemiology.Here, we reviewed the progress of MNT in the field of molecular cancer epidemiology in recent years, including early detection and diagnosis of cancer, evaluation of carcinogenic substances, genetic susceptibility biomarkers, micronutrient and cohort studies.
