Meta-analysis of the relationship between soybean product consumption and gastric cancer.

Xing TONG; Wei LI; Li-qiang QIN

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Meta-analysis of the relationship between soybean product consumption and gastric cancer.

Author: Xing TONG ¹ ; Wei LI ; Li-qiang QIN
Author Information

1. Department of Nutrition and Food Hygiene, School of Radiation Medicine and Public Health, Soochow University, Suzhou, Jiangsu 215123, China.
Publication Type:Journal Article
MeSH: Cohort Studies; Feeding Behavior; Humans; Odds Ratio; Soy Foods; Stomach Neoplasms; epidemiology
From: Chinese Journal of Preventive Medicine 2010;44(3):215-220
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo study the effects of soybean products consumption on the risk of gastric cancer.
METHODSLiteratures published in English and Chinese reporting the relationship between soybean product consumption and gastric cancer from 1988 to 2008 were searched in this study. Fifty-three relevant articles were selected and 28 of them met the criteria. Meta-analysis was applied to estimate the combined odds ratio (OR) and 95% confidence interval (95%CI) between soybean product consumption and gastric cancer.
RESULTSA total of 28 independent studies were selected including 16 case-control studies, 10 cohort studies and 2 cross sectional studies. The random-effect model was used due to the heterogeneity among these studies. The overall ORs (95%CI) of Meta-analysis on subjects who consumed soybean products, tofu and miso were 0.58 (0.52 - 0.65), 0.90 (0.80 - 1.00) and 1.18 (1.09 - 1.28), respectively.
CONCLUSIONConsumption of soybean products and tofu was inversely associated with gastric cancer, while miso consumption could increase the risk to gastric cancer.