A Meta analysis: mother to infant transmission of hepatitis B virus via different combined immunoprophylaxis delivery modes.
- Author:
Hui-hua WANG
1
;
Zheng-ping WANG
Author Information
- Publication Type:Journal Article
- MeSH: Delivery, Obstetric; methods; Female; Hepatitis B; prevention & control; transmission; Hepatitis B Vaccines; therapeutic use; Hepatitis B virus; Humans; Immunization; Infant; Infectious Disease Transmission, Vertical; prevention & control; Pregnancy
- From: Chinese Journal of Preventive Medicine 2010;44(3):221-223
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate the effect of different combined immunoprophylaxis delivery modes on mother to infant transmission of hepatitis B virus (HBV).
METHODSSix hundred and ninety-six relevant literatures were collected by systematic literature search. Meta-analysis was applied to seven selected literatures that met the criteria and to assess the influence on the infant HBV transmission via different delivery patterns by infants combined immunoprophylaxis.
RESULTSA total of 1435 cases from seven studies which met the criteria were included. The positive rate of HBV was 7.34% (61/831) among the 831 infants in the vaginal delivery group and 4.80% (29/604) among the 604 infants in the caesarean section group. There was no statistically difference between the two groups (OR = 0.70, 95%CI: 0.45 - 1.11, Z = 1.52, P = 0.13).
CONCLUSIONThere was no significant effect of delivery modes on infant infectious rate of HBV by infants' passive and active immunization.
