Clinical and laboratory investigation of four acute myeloid leukemia patients with t(3;3) translocation.
- Author:
Zhi-mei CHEN
1
;
Jian-guo WU
;
Jie JIN
;
Ji-yu LOU
;
Mao-fang LIN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Chromosomes, Human, Pair 3; Female; Humans; Karyotyping; Leukemia, Myeloid, Acute; genetics; Male; Middle Aged; Prognosis; Translocation, Genetic
- From: Chinese Journal of Hematology 2004;25(1):35-37
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the clinical and laboratory characteristics of four acute myeloid leukemia with t(3;3) translocation.
METHODSBone marrow cell chromosome karyotype analysis were carried out with direct method and short-term culture and R-banding technique.
RESULTSFour AML patients with t(3;3) translocation were identified. They did not obtain complete remission after chemotherapy and the median survival time was 4.5 months.
CONCLUSIONSt(3;3) translocation is a rare chromosome abnormality, which has mostly been found in myeloid leukemia and the prognosis of these patients is poor.
