Retrospective real world study to explore use of parenterally administered kudiezi in combination with other medications based on hospital information study data.
- Author:
Xing LIAO
1
;
Xian-Bin ZENG
2
;
Yan-Ming XIE
3
;
Wei YANG
3
;
Yan-Peng CHANG
3
Author Information
- Publication Type:Journal Article
- MeSH: Adolescent; Adult; Aged; Aged, 80 and over; Cerebral Infarction; drug therapy; mortality; Coronary Artery Disease; drug therapy; mortality; Drug Therapy, Combination; Drugs, Chinese Herbal; administration & dosage; Female; Hospital Information Systems; statistics & numerical data; Humans; Infusions, Parenteral; Male; Middle Aged; Pragmatic Clinical Trials as Topic; Retrospective Studies; Young Adult
- From: China Journal of Chinese Materia Medica 2013;38(18):3110-3115
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEParenterally administered Kudiezi (KDZ) is used in real world clinical situations to treat coronary heart disease and cerebral infarction. This paper analyzes its clinical use with other drug combinations. Clinicians' experiences of using such treatments are also referred to.
METHODHospital information system (HIS) data from 18 hospitals, comprising records of 6 032 patients with Coronary heart disease and 3 468 patients with cerebral infarction were analyzed.
RESULTComparison and analysis between varying courses of KDZ plus different drug combinations was carried out. The mean single dose of KDZ, death rate and improvement rates along with drug combinations were ascertained with various illustrations given.
CONCLUSIONAlthough data showed some clinical correlations between factors analyzed, strong causal relationships are yet to be found. Hence, there is a need for further exploration and analysis.
