Based on propensity score methods analysis of outcomes of parenterally administered shuxuetong in treatment of cerebral infarction.
- Author:
Jun-Jie JIANG
1
;
Lin LI
2
;
Yan-Ming XIE
3
;
Hu YANG
2
;
Yan ZHUANG
4
Author Information
1. Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China. studentjiangjunjie@163.com
2. Renmin University of China, Beijing 100872, China.
3. Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences, Beijing 100700, China.
4. The PLA Navy General Hospital, Beijing 100048, China.
- Publication Type:Journal Article
- MeSH:
Adolescent;
Adult;
Aged;
Aged, 80 and over;
Cerebral Infarction;
drug therapy;
Drugs, Chinese Herbal;
administration & dosage;
Female;
Hospital Information Systems;
statistics & numerical data;
Humans;
Male;
Middle Aged;
Outcome Assessment (Health Care);
Pragmatic Clinical Trials as Topic;
Propensity Score;
Treatment Outcome;
Young Adult
- From:
China Journal of Chinese Materia Medica
2013;38(18):3180-3185
- CountryChina
- Language:Chinese
-
Abstract:
Hospital information system (HIS) data from 18 hospitals was analyzed. 107 723 cases were divided into two groups, those that received Shuxuetong and those that did not. Patients, 18 to 80 years old, suffering from cerebral infarction, whose treatment outcome was clear were selected. Resulting in 7 520 cases in the treatment group and 3 353 who did not receive parenterally administered Shuxuetong. Using propensity score, confounding factors were balanced between the two groups, three logistic regression methods were used to compare the groups following treatment for cerebral infarction. The three methods of comparison indicated that the use of Shuxuetong significantly increased cure rates compared to the control group. Therefore, based on existing data, for the treatment of cerebral infarction, the outcomes are more effective when combination therapy including Shuxuetong is used.