Lentiviral vectors and advance in its application.
- Author:
Bo CHU
1
;
Xuefeng HUANG
;
Yunming TANG
Author Information
1. School of Life Science of Southwest University, Chongqing 400715, China.
- Publication Type:Journal Article
- MeSH:
Animals;
Animals, Genetically Modified;
Genetic Therapy;
methods;
trends;
Genetic Vectors;
genetics;
HIV-1;
genetics;
Humans;
RNA, Small Interfering;
genetics;
Transduction, Genetic;
methods
- From:
Journal of Biomedical Engineering
2008;25(1):224-226
- CountryChina
- Language:Chinese
-
Abstract:
Lentiviral vectors (Lv), known as holding lots of virtues (e.g. transfection to the dividing or non-dividing cells;large capacity of transfer gene fragments; long-term expression transfer genes; and low rate of immunological response) has come to be one of the hot-spots in gene therapy research. In this paper, taking the Lv derived from HIV-1 for example, we review the characteristics of frame, the developments and the advances in application of Lv.
