Studies on crosslinkable coatings for biomedical application.
- Author:
Jian JI
1
;
Weidong CHEN
;
Jianping XU
;
Jiacong SHEN
;
Dezeng FANG
;
Fuyu SUN
Author Information
1. Department of Polymer Science and Composite Materials, Zhejiang University, Hangzhou 310027, China. jianji@mail.hz.zj.cn
- Publication Type:Journal Article
- MeSH:
Blood Coagulation;
Coated Materials, Biocompatible;
chemistry;
Cross-Linking Reagents;
chemistry;
Materials Testing;
Platelet Adhesiveness;
Polyethylene Glycols;
chemistry;
Surface Properties
- From:
Journal of Biomedical Engineering
2004;21(1):122-125
- CountryChina
- Language:Chinese
-
Abstract:
A novel crosslinkable coating for biomedical device was prepared by copolymerization of the constituent monomers via a free radical method. 1H-NMR and IR results indicated it had desirable structure. Surface characterization revealed that surface reorganization occurred in aqueous environment and a polyethylene oxied (PEO) enrichment surface was developed on coated surface. The in-vitro platelet-adhesion test and the plasma recalcification time(PRT) determination showed that the coated surface could resist the blood coagulation effectively.
