Detection of early organ dysfunction for the selection of treatment strategy on severe acute pancreatitis..
- Author:
Yi-Fan LU
1
;
Ruo-Qing LEI
;
Zhi-Wei XU
;
Yang DENG
;
Sheng CHEN
;
Hong-Chang LI
;
Chun-Yu CHAI
;
Tian-Quan HAN
;
Yao-Qing TANG
;
Sheng-Dao ZHANG
Author Information
- Publication Type:Journal Article
- MeSH: Acute Disease; Aging; Humans; Multiple Organ Failure; Pancreatitis; diagnosis; Prognosis
- From: Chinese Journal of Surgery 2009;47(19):1455-1458
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the severity related influencing factor and treatment strategy of severe acute pancreatitis with early organ dysfunction.
METHODSFrom July 2007 to December 2008, 167 patients with severe acute pancreatitis were treated in the Surgical Department of Ruijin Hospital. The relationships between the happening of early organ dysfunction and outcome of the patients were observed, with operative or nonoperative treatment strategy.
RESULTSAmong 167 patients, 68 patients have early organ dysfunction, in which 39 with single organ dysfunction and 29 with multiple organ dysfunction. The early organ dysfunction were involved in 47.1% in cardiovascular system, 35.3% in lung and 29.4% in kidney. Aging (P < 0.05) and higher APACHE II score (P < 0.05) predicted a poor prognosis, which were benefit from early operation.
CONCLUSIONSThe mortality of the patients with SAP is related to age, and the degree of organ dysfunction as well. In the first phase of the disease, the selection of operation depends on the trends and the degree of early organ dysfunction before infected necrosis happens, with the aid of SOFA score as a scale.
