Excitatory postsynaptic potential evoked by stimulation of the ventrolateral region of the cerebellum in crucian carp Mauthner cell.
- Author:
Ying-Cai ZHANG
1
;
Shu-Hua ZHANG
;
Xiao-Yi LI
;
Xue-Hong TONG
;
Fen YU
;
Mao-Xian ZHANG
Author Information
1. Department of Physiology, Capital University of Medical Sciences, Beijing 100054. tsaizh@263.net
- Publication Type:Journal Article
- MeSH:
Animals;
Carps;
physiology;
Cerebellum;
physiology;
Dendrites;
physiology;
Electric Stimulation;
Excitatory Postsynaptic Potentials;
physiology;
Neurons;
physiology;
Synapses;
physiology;
Synaptic Transmission;
physiology
- From:
Acta Physiologica Sinica
2003;55(4):459-463
- CountryChina
- Language:Chinese
-
Abstract:
In the present experiments, the characteristics of the electrical responses to stimulation of the cerebellum in crucian carp Mauthner cell were explored with microeletrode intracellular recording technique. A composite excitatory postsynaptic potential (cerebellum-evoked EPSP) could be induced from the soma, the ventral dendrite and the proximal end of the lateral dendrite in crucian carp Mauthner cell (M-cell) on either side by stimulation of the ventrolateral region of the cerebellum. The cerebellum-evoked EPSP presented characteristics of relatively short latency (0.63+/-0.09 ms), longer duration (5.49+/-1.13 ms), graded amplitude and dependence on stimulation frequency. Stimulation of the cerebellum with higher intensity always activated the M-cell orthodromically. Multiple intracellular recordings showed that the cerebellum-evoked EPSP originated in the distal end of the ventral dendrite. The results suggest that the cerebellum-M-cell pathway is probably composed of a group of neuron chains with different numbers of synaptic relays projecting to the distal end of the ventral dendrite in order of length of the chains.
