Clinicopathological features and prognosis of colorectal cancer patients with preoperative cancer-related anemia.
- Author:
Yi-sheng WEI
1
;
Chu-yuan HONG
;
Chu-xiong ZHAO
;
Guo-jian LIANG
;
Guo-qiang WANG
;
Xiang-cai ZOU
;
Hang LIN
Author Information
- Publication Type:Journal Article
- MeSH: Adult; Aged; Aged, 80 and over; Anemia; etiology; Colorectal Neoplasms; complications; surgery; Female; Humans; Male; Middle Aged; Prognosis; Retrospective Studies; Young Adult
- From: Chinese Journal of Gastrointestinal Surgery 2012;15(4):385-387
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo analyze the clinicopathological features and prognosis of colorectal cancer patients with preoperative cancer-related anemia.
METHODSClinical data of 354 patients with colorectal cancer in the Second Affiliated Hospital of Guangzhou Medical College from January 2003 to July 2009 were analyzed retrospectively. Those with hemoglobin(Hb)<120 g/L before surgery were defined as cancer-related anemia.
RESULTSOf the 354 colorectal cancer cases, 195 were males and 159 were females. The median age was 65(range 22-92) years. Preoperative cancer-related anemia tended to be occurred in female(P<0.01) and those with preoperative albumin ≤35 g/L (P<0.01), right colon cancer(P<0.01) and full-thickness invasion(P<0.05). Cox regression analysis showed preoperative cancer-related anemia was an independent unfavorable factor for overall survival (HR=1.60, 95% CI:1.05-2.44; P<0.05), but not for disease-free survival (HR=1.43, 95% CI:0.97-2.12; P>0.05) in colorectal cancer.
CONCLUSIONSPreoperative cancer-related anemia plays an important role in the development and prognosis of colorectal cancer and great attention should be paid to clinical practice.
