Comparison of four domestic quantity assay reagents for detecting the weak-reactive results of HBsAg.
10.3760/cma.j.issn.1007-3418.2011.02.006
- Author:
Ling-Li JIANG
1
;
Hui-Ying CHEN
;
Yan-Qun XIAO
;
Yin-Hua LU
;
Wei-Jie SHAO
;
Min-Hua JIAN
;
Chong XU
;
Jian ZHANG
Author Information
1. Shanghai Centre for Clinical Laboratory, Shanghai 200126, China.
- Publication Type:Journal Article
- From:
Chinese Journal of Hepatology
2011;19(2):98-101
- CountryChina
- Language:Chinese
-
Abstract:
To evalue the coincidence and correlation between the four domestic quantity assay reagents and with ARCHITECTi2000 immunoassay system. 185 weak-reactive serum samples and standard materials of different concentrations were tested by four domestic quantity assay reagents for HBsAg test and ARCHITECTi2000 immunoassay system. The coincidence, the precision and the correlations between different systems were analyzed. The coincidence rates of the results of 0.05-1.00 IU/ml samples between the four domestic quantity assay reagents and ARCHITECTi2000 immunoassay system were 25.93%, 35.19%, 51.85% and 18.52% respectively, and for those results of more than 1.00 to 10.00 IU/ml samples the coincidence rates were 71.76%, 87.79%, 95.42% and 69.47% respectively. The samples of 0.05 to 0.80 IU/ml weak-reactive serum samples detected by the i2000 system were all negative detected by the four domestic systems. The coincidence rates of more than 7.93 IU/ml serum samples detected by i2000 system were 100% detected by the four domestic systems. The correlations of the four domestic quantity assays were around 0.8629 to 0.9265. The analysis sensitivity of the four domestic quantity assay reagents were below the i2000 system. The results of under 0.80 IU/ml samples detected by i2000 system were disaccord with the results detected by the four domestic systems, whereas for the sapmples over 7.93 IU/ml the results were consistent.
