Prevention of neurotoxicity by high-dose folinic acid rescue after high-dose methotrexate and intrathecal methotrexate without compromising cure inspite of previous transient leukoencephalopathy after intrathecal methotrexate.
- Author:
Alias HAMIDAH
;
Raja Juanita Raja LOPE
;
Zarina Abdul LATIFF
;
Zulfiqar M ANUAR
;
Rahman JAMAL
- Publication Type:Case Reports
- MeSH:
Child;
Folic Acid;
administration & dosage;
therapeutic use;
Folic Acid Antagonists;
adverse effects;
Hematinics;
administration & dosage;
therapeutic use;
Humans;
Hypesthesia;
chemically induced;
drug therapy;
Injections, Spinal;
Leukoencephalopathies;
chemically induced;
Male;
Methotrexate;
adverse effects;
Quadriplegia;
chemically induced;
drug therapy;
Time Factors;
Vitamin B Complex;
administration & dosage;
therapeutic use
- From:Annals of the Academy of Medicine, Singapore
2009;38(8):743-744
- CountrySingapore
- Language:English