Evaluation of milk intake and calcium supplement on bone mineral density and growth in children through Meta-analysis.
- Author:
Nan LI
1
;
Yin WANG
;
Shi-an YIN
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Body Height; drug effects; Body Weight; drug effects; Bone Density; drug effects; Bone Development; drug effects; Calcium, Dietary; administration & dosage; pharmacology; Child; Dietary Supplements; Humans; Milk; Randomized Controlled Trials as Topic
- From: Chinese Journal of Preventive Medicine 2007;41(3):172-175
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVEBased on peer-reviewed random-control studies, effects of calcium supplement and intake of milk on bone mineral density (BMD) and growth in children were evaluated.
METHODSMeta-analysis was applied to review published data in random-control studies related to the effects of calcium supplement and milk consumption on BMD, body height and body weight in children.
RESULTSEleven peer-reviewed papers published during 1993 to 2006 were selected in this study. Homogeneity test showed that random effect model should be selected for weighting and pooling data. The combined means of improvement in BMD, height and body weight in children with milk intervention were 2.01 (0.92 - 3.09), 0.25 (0.09 - 0.41) and 0.63 (0.33 - 0.93), respectively, and the data from children with calcium intervention were 1.05 (0.66 - 1.43), -0.10 (-0.25 - 0.05) and -0.75 (-1.98 - 0.49), respectively.
CONCLUSIONBoth milk and calcium intakes could improve BMD of children significantly, and the difference in BMD gain through milk intake was the same as that with calcium intervention, however, compared with the control group, increasing milk intake did significantly promote growth and development of children compared to the calcium supplement group.