Sibutramine (Reductil(R))-Induced Cutaneous Leukocytoclastic Vasculitis: A Case Report.
- Author:
You Jin HA
1
;
You Jin HAN
;
You Won CHOI
;
Ki Bum MYUNG
;
Hae Young CHOI
Author Information
- Publication Type:Case Report
- Keywords: Cutaneous leukocytoclastic vasculitis; Drug induced vasculitis; Sibutramine
- MeSH: Biopsy; Cyclobutanes; Eosinophils; Female; Humans; Leg; Lower Extremity; Skin; Vasculitis; Vasculitis, Leukocytoclastic, Cutaneous
- From:Annals of Dermatology 2011;23(4):544-547
- CountryRepublic of Korea
- Language:English
- Abstract: A 24-year old woman presented with hemorrhagic vesicles on her legs. She had taken sibutramine (Reductil(R), Abbott Labs., Seoul, South Korea) for 3 months and developed skin lesions the week before. A skin biopsy showed leukocytoclastic vasculitis with conspicuous eosinophilic infiltration of the tissue. These lesions showed improvement after discontinuation of sibutramine. However, 3 months later the skin lesions recurred on other sites on the lower extremities when the patient was rechallenged with the same drug for 2 weeks. Herein, we report the first case of necrotizing vasculitis induced by sibutramine.
