Effects of the blood glucose-adjusting recipe on blood glucose and pancreas islet pathology in diabetic mice.
- Author:
Su-fang LUO
1
;
Yu-yao CHEN
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Blood Glucose; drug effects; Diabetes Mellitus, Experimental; blood; drug therapy; pathology; Drugs, Chinese Herbal; therapeutic use; Islets of Langerhans; pathology; Mice; Phytotherapy
- From: Journal of Southern Medical University 2010;30(4):847-850
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo study the effects of a self-formulated blood glucose-adjusting recipe on blood glucose and pathology of the pancreas in diabetic mice.
METHODSDiabetes mellitus (DM) was induced in mice by injection of alloxan through the caudal vein. The blood glucose-adjusting recipe was administered in the mice at the doses of 20, 10 and 5 g/kg for 21 days, after which blood glucose was determined and the sugar tolerance was evaluated, and the pancreas and islet pathologies were examined microscopically.
RESULTSThe blood glucose-adjusting recipe at 20 g/kg significantly lowered the fast blood glucose in the mice, and at 20 and 10 g/kg, the recipe significantly lowered the blood glucose 2 h after glucose administration and increased the sugar tolerance. The pathological damage in the diabetic mice was alleviated after treatment with the recipe.
CONCLUSIONSThe blood glucose-adjusting recipe has a good effect in stabilizing blood glucose in mice.
