Acute panautonomic neuropathy: a report of 4 cases.
- Author:
Fang CUI
1
;
Xu-sheng HUANG
;
Zhi-bin ZHOU
Author Information
- Publication Type:Case Reports
- MeSH: Acute Disease; Adolescent; Adrenal Cortex Hormones; therapeutic use; Adult; Autonomic Nervous System Diseases; diagnosis; physiopathology; therapy; Female; Humans; Immunoglobulins, Intravenous; therapeutic use; Male; Young Adult
- From: Journal of Southern Medical University 2010;30(4):900-902
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo explore the clinical manifestations, diagnosis, treatment and prognosis of acute panautonomic neuropathy (APN).
METHODSWe reviewed the history, clinical findings, electrophysiological characteristics, laboratory features of CSF and treatment of 4 patients with APN.
RESULTSAll these patients showed acute onset with apparent involvement of the autonomic nervous system. The clinical features of autonomic involvement included fixed dilated pupils, abdominal pain, diarrhea, and anhidrosis. Electromyography showed evidence of peripheral neuropathy. Early treatment with corticosteroid and intravenous immunoglobulins resulted in improved prognosis of the patients.
CONCLUSIONAPN is a rare autonomic nervous system disorder, and understanding of the clinical features may help in early diagnosis and treatment of the patients.