Optical coherence tomography for evaluation of neointimal proliferation after placement of a new drug eluting stent.
- Author:
Chang-fu LIU
1
;
Yun-dai CHEN
;
Lian CHEN
;
Zhi-jun SUN
;
Lu-yue GAI
;
Hong-bin LIU
;
Feng TIAN
;
Qi-cai BAI
;
Kai GUO
Author Information
- Publication Type:Journal Article
- MeSH: Angioplasty, Balloon, Coronary; adverse effects; Cell Proliferation; Coronary Artery Disease; pathology; therapy; Coronary Vessels; pathology; Drug-Eluting Stents; adverse effects; Humans; Prospective Studies; Tomography, Optical Coherence; Tunica Intima; pathology
- From: Journal of Southern Medical University 2010;30(5):1063-1065
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo evaluate neointimal proliferation following placement of a new drug-eluting stent (BUMA) by optical coherence tomography (OCT).
METHODSTwenty-two patients with coronary artery disease were randomized into BUMA group (n=15) and Endeavor group (n=7) and underwent OCT imaging after 9 months of stent implantation.
RESULTSThe neointima hyperplasia (NIH) thickness in BUMA group were significantly smaller than that in endeavor group (0.220-/+0.140 mm vs 0.269-/+0.207 mm, P<0.001), and the uncovered Struts were significantly lower in BUMA group than in Endeavor group (5.65% vs 6.56%, P<0.0001). The luminal late loss in BUMA group was also significantly lower (34.87-/+11.50 vs 40.82-/+18.53, P=0.025).
CONCLUSIONBUMA stent is safe and effective for treatment of coronary artery disease.
