Application of Reporter Gene Labeling in Stem Cell Therapy for Acute Myocardial Infarction.
10.3881/j.issn.1000-503X.2015.05.021
- Author:
Xiao LI
1
;
Zheng-yu JIN
1
;
Yi-ning WANG
1
Author Information
1. Department of Radiology,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
- Publication Type:Journal Article
- MeSH:
Genes, Reporter;
Genetic Therapy;
Humans;
Myocardial Infarction;
Stem Cell Transplantation
- From:
Acta Academiae Medicinae Sinicae
2015;37(5):612-617
- CountryChina
- Language:Chinese
-
Abstract:
Stem cell therapy for acute myocardial infarction is drawing great attention. However,the biological behavior and function mechanism of implanted stem cells remain controversial, as well as their clinical benefits. With the development of imaging probes and devices, molecular imaging enables noninvasive, dynamic tracking of stem cells in vivo. In this review, we summarize the use of various markers,especially the technique of reporter gene labeling, in the field of stem cell therapy, and highlight some recent preclinical and clinical achievements.
