Potential Clinical Implications of Circulating Tumor Cells.
10.3881/j.issn.1000-503X.2015.05.023
- Author:
Wen-jun LIAO
1
;
Yi-lei MAO
1
Author Information
1. Department of Liver Surgery,PUMC Hospital,CAMS and PUMC,Beijing 100730,China.
- Publication Type:Journal Article
- MeSH:
Cell Separation;
Disease Progression;
Humans;
Neoplastic Cells, Circulating;
Prognosis
- From:
Acta Academiae Medicinae Sinicae
2015;37(5):623-627
- CountryChina
- Language:Chinese
-
Abstract:
The circulating tumor cells (CTCs) are derived from primary or metastatic tumor lesions and can be detected in the peripheral blood. With certain specific features, CTCs can,to certain extent, reflect the progression and invasiveness of tumors. Detection of CTCs may provide a powerful and noninvasive approach for diagnosing neoplastic disease, identifying drug sensitivity, and enabling real-time treatment monitoring and prognosis prediction. Improvements in cell isolation and molecular identification will enable a broad range of clinical applications.