The ameliorate effect of anthocyanin onMouse testis damage.

Author: Pin GONG ¹ ; Fuxin CHEN ; Jing WANG ; Sai JIN ; Yangmin MA ²
Author Information

1. Key Laboratory of Auxiliary Chemistry & Technology for Light Chemical Industry, Ministry of Education, College of Life Science and Technology, College of Chemistry and Chemical Engineering, Shaanxi University of Science and Technology, Xi'an 710021, China.
2. E-mail: mym63@sina.com.
Publication Type:Journal Article
MeSH: Animals; Anthocyanins; chemistry; pharmacology; Cadmium; toxicity; Catalase; drug effects; Male; Malondialdehyde; analysis; Mice; Oxidative Stress; Protein Carbonylation; drug effects; Superoxide Dismutase; drug effects; Testis; drug effects
From: Chinese Journal of Industrial Hygiene and Occupational Diseases 2014;32(10):762-764
CountryChina
Language:Chinese
Abstract:
OBJECTIVETo study the effect of Anthocyanin (Ay) on Cadmium-Induced Mouse testis Damage.
METHODSMouse testis damage model were constructed and testis malonaldehyde (MDA) and protein carbonxyl content (PCO), as well as catalase (CAT) and superoxide dismutase (SOD) were determined.
RESULTSThe intoxication of cadmium can cause the increase of MDA and PCO content in mouse testis (P < 0.05), however, the activities of SOD and CAT were altered (P < 0.01).
CONCLUSIONAy have the strong potent to scavenge free radicals, owing to its special chemical structures, and act as a protector to inhibit the oxidative stress induced by cadmium.