Relationship between white blood cell count, neutrophils ratio and erythrocyte sedimentation rate and short clinical outcomes among patients with acute ischemic stroke at hospital admission
10.3760/cma.j.issn.0254-6450.2012.09.018
- VernacularTitle:白细胞计数、中性粒细胞比率和红细胞沉降率与急性脑梗死结局的关系
- Author:
Jia-Kai YE
1
;
Jin-Tao ZHANG
;
Yan KONG
;
Tan XU
;
Ting-Ting ZOU
;
Yong-Hong ZHANG
;
Shao-Yan ZHANG
Author Information
1. 苏州大学医学部公共卫生学院流行病学教研室
- Keywords:
Stroke;
White blood cell count;
Neutrophils ratio;
Erythrocyte sedimentation rate
- From:
Chinese Journal of Epidemiology
2012;33(9):956-960
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship between white blood cell count,neutrophils ratio and erythrocyte sedimentation rate and short outcomes among patients with acute ischemic stroke at admission to the hospital.Methods A total of 2675 acute ischemic stroke patients were included in this study.Data on demographic characteristics,life style,history of disease,white blood cell count( WBC),neutrophils ratio(NEUR),erythrocyte sedimentation rate(ESR) and clinical outcomes were collected for all the participants.Poor clinical outcome was defined as neurologic deficiency (NIHSS≥5) at discharge or death during hospitalization.Results White blood cell count,neutrophils ratio and erythrocyte sedimentation rate were higher in patients with poor outcome than m those without clinical outcome.According to the quartile range,WBC,NEUR and ESR were divided into four levefs at admission.After adjustment for multivariate,compared with WBC≤5.6 × 109/L,the odds ratio (95％ confidence intervals) of poor outcome with ≥8.7 × 109/L was 1.883 (1.306-2.716).When compared with NEUR≤0.56,the odds ratio (95％ confidence intervals) of poor outcome with 0.57-0.64 and with ≥0.74 were 1.572 (1.002-2.466) and 2.577 ( 1.698-3.910),respectively.When compared with ESR≤4 mm/h,the odds ratio (95％ confidence intervals) of poor outcome with ≥17 mm/h was 2.426 (1.233-4776).Elevated WBC count and NEUR at admission were significantly and positively associated with poor clinical outcomes among patients with acute ischernic stroke (trend test P＜0.05).Elevated ESR was not significantly or positively associated with poor clinical outcomes among patients with acute ischemic stroke (trend test P＞0.05).Conclusion There appeared associations between WBC,NEUR,ESR and poor outcome among patients with acute ischemic stroke at admission to the hospital.Both elevated WBC count and NEUR showed significantly positive association with poor clinical outcomes among patients with acute ischemic stroke at admission.
