Investigation on the source of infection regarding an avian influenza (H5N1) case in Hong Kong that returning from Guangzhou
10.3760/cma.j.issn.0254-6450.2012.11.014
- VernacularTitle:一例H5N1人禽流感病例感染源调查分析
- Author:
Jun YUAN
1
;
Yu-Fei LIU
;
Kui-Biao LI
;
Jie ZHOU
;
Chao-Jun XIE
;
Wen-Feng CAI
;
Jie-Yun PAN
;
Qing-Lian LIU
;
Xiao-Ling XIAO
;
Biao DI
;
Jian-Ping LIU
;
Xiao-Wei MA
;
Yan-Hui LIU
;
Zhi-Cong YANG
Author Information
1. 510440,广州市疾病预防控制中心
- Keywords:
Avian influenza;
Epidemiology investigation;
Infection sources
- From:
Chinese Journal of Epidemiology
2012;33(11):1159-1162
- CountryChina
- Language:Chinese
-
Abstract:
Objective We conducted an epidemiologic investigation to determine the source of infection on an avian influenza (H5N1) case who returned from Guangzhou,in Hong Kong.Methods Data related to epidemiologic investigation,medical observation on close contacts,Syndromic Surveillance on poultry salesmen,emergency monitoring,detection of the samples,source tracing on potential Avian influenza virus (H5,H7,H9) infected people,situation on environment pollution by avian influenza virus in the markets etc.were gathered.The determination of infection source was through comparing the different genes between the case and positive environmental samples.Results The infected case witnessed the procedure of how a live duck was killed,in market A in Guangzhou during May 17th to 19th.The case was diagnosed as respiratory tract infection in 2 Third-grade-Class A hospitals in Guangzhou on May 23th and 24th.The diagnosis was made as Avian influenza cases on May 26th after going back to Hong Kong.23 close contacts and 34 markets poultry salesmen did not show any ILI related symptoms.However,2 poultry salesmen from the markets nearby the place where the Avian influenza case stayed,were detected having positive H9 avian influenza antibody,with the H9 positive rate as 6.06％ (2/33).Among the environmental samples in the 2 markets nearby home of the patient,chopping block was found to have carried H5,with positive rate as 9.8％(5/51) while poultry cage was found to carry H9,with the positive rate as 2.0％(1/51).A H5 positive sample was found with clade 2.3.2.1,same to the case,from a chopping block at the market B where the sources of poultry was the same as market A.Conclusion The source of infection seemed to come from the markets in Guangzhou,that calling for the strengthening of poultry market management,for avian influenza prevention.History related to contact of poultry should be gathered when a diagnosis of respiratory tract infection was made.Timely sampling and testing should be made to improve the sensitivity of diagnosis.
