Tests of bioavailability in vivo - a method of evaluating the drug real quality
- Author:
Vinh Thi Phung
- Publication Type:Journal Article
- Keywords:
drug quality
- MeSH:
Pharmaceutical Preparations;
Quality Control;
Biological Availability
- From:Pharmaceutical Journal
2001;298(2):4-7
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Some standards in vivo such as physical and chemical properties, stability, water content, disintegration, dissolution are regular standards of drug quality control. These parameters indicated that the drug manufactured according to procedure. But the parameters of bioavailability in vivo demonstrate the real quality of the drug. They comprise the area under curve (AUC), maximum concentration (Cmax) and time for reaches the Cmax(Tmax). Model of experimental animals play an important role in the tests of bioavailability and bioequivalence.
