Assessing a Dysplastic Cerebellar Gangliocytoma (Lhermitte-Duclos Disease) with 7T MR Imaging.
10.3348/kjr.2010.11.2.244
- Author:
Christoph MOENNINGHOFF
1
;
Oliver KRAFF
;
Marc SCHLAMANN
;
Mark E LADD
;
Zaza KATSARAVA
;
Elke R GIZEWSKI
Author Information
1. Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Germany. ch.moenninghoff@uk-essen.de
- Publication Type:Case Report
- Keywords:
Lhermitte-Duclos disease;
7 Tesla;
Magnetic resonance (MR);
Dysplastic cerebellar gangliocytoma;
Susceptibility-weighted imaging
- MeSH:
Cerebellar Cortex/pathology;
Cerebellar Neoplasms/complications/*pathology;
Diagnosis, Differential;
Gait Ataxia/etiology;
Hamartoma Syndrome, Multiple/complications/*pathology;
Humans;
Image Processing, Computer-Assisted/methods;
Magnetic Resonance Imaging/*methods;
Magnetic Resonance Spectroscopy/methods;
Magnetics;
Male;
Middle Aged;
Vertigo/etiology
- From:Korean Journal of Radiology
2010;11(2):244-248
- CountryRepublic of Korea
- Language:English
-
Abstract:
Lhermitte-Duclos disease (LDD; dysplastic cerebellar gangliocytoma) is a rare hamartomatous lesion of the cerebellar cortex and this was first described in 1920. LDD is considered to be part of the autosomal-dominant phacomatosis and cancer syndrome Cowden disease (CS). We examined the brain of a 46-year-old man, who displayed the manifestations of CS, with 7 Tesla (T) and 1.5T MRI and 1.5T MR spectroscopy (1H-MRS). We discuss the possible benefits of employing ultrahigh-field MRI for making the diagnosis of this rare lesion.