Expression and role of nitric oxide synthase in the testis and epididymis of Macaca fascicularis.
- Author:
Li SUN
1
;
Ya-Ping REN
;
Wei JIANG
;
Mei-Yan ZHANG
;
Qiao-Yan HOU
Author Information
- Publication Type:Journal Article
- MeSH: Animals; Epididymis; metabolism; Immunohistochemistry; Macaca fascicularis; Male; Nitric Oxide Synthase; biosynthesis; physiology; Testis; metabolism
- From: National Journal of Andrology 2006;12(10):876-878
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVETo investigate the expression and the role of nitric oxide synthase (NOS) in the testis and epididymis of macaca fascicularis.
METHODSThe immunohistochemical ABC method was used to observe the localization of nitric oxide synthase in the testis and epididymis of the macaca fascicularis.
RESULTS(1) nNOS immunoreactivity was found in the spermatogenic cells of seminiferous tubules, the epithelia of epididymal efferent ducts, sperm and the endothelia of blood vessels; (2) iNOS was expressed in the epididymal efferent duct, the sperm inside the duct, and the myoid cells and endothelia of blood vessels; (3) eNOS immunoreactivity was detected in the interstitial cells of the testis, the epididymal efferent duct, the sperm inside the duct, and the myoid cells and endothelia of blood vessels.
CONCLUSIONNOS is extensively expressed in the testis and epididymis of the macaca fascicularis and it may play an important role in such processes as spermatogenesis, sperm maturation and testosterone secretion.
